1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Cytochrome-B(5) Reductase
|
Descriptor Spanish:
|
|
Citocromo-B(5) Reductasa
|
Descriptor Portuguese:
|
|
Citocromo-B(5) Redutase
|
Synonyms English:
|
|
Methemoglobin Reductase
NADH Cytochrome B5 Reductase
NADH Methemoglobin Reductase
NADH-Cytochrome B5 Reductase
NADH-Ferrihemoglobin Reductase
B5 Reductase, NADH-Cytochrome
Methemoglobin Reductase, NADH
NADH Ferrihemoglobin Reductase
Reductase, Methemoglobin
Reductase, NADH Methemoglobin
Reductase, NADH-Ferrihemoglobin
|
Tree Number:
|
|
D08.811.682.608.191.237
D12.776.331.186
|
Definition English:
|
|
A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA. |
Indexing Annotation English:
|
|
/defic: consider also METHEMOGLOBINEMIA
|
History Note English:
|
|
2004; use CYTOCHROME B(5) REDUCTASE (NM) 1980-2003
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
38212
|
Unique Identifier:
|
|
D042966
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 LILACS
|